Injectable therapy for Peyronie’s disease
نویسندگان
چکیده
Peyronie's disease is a disfiguring and psychologically devastating disease, which continues to pose a significant clinical conundrum to the attending doctor. Many forms of therapy have been trialled but results have been inconsistent at best. Non-surgical therapy revolves around oral, intralesional and shockwave therapies. The focus of this paper is on intralesional agents, their evolution and efficacy of treatments. The mere fact that so many agents have been tried is a testament to the incomplete knowledge that we have with regards to the underlying pathophysiology of the disease. Currently, the only U.S. Food and Drug Administration (FDA) approved agent that has shown fairly consistent results is Clostridium histiolyticum collagenase (Xiaflex(TM)), whereas calcium channel blockers and interferons (IFN) remain as off-label options.
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استفاده از اتوگرافت تونیکا آلبوژینه کرورا اجسام غاری جهت درمان بیماری پیرونی: نتایج پیگیری یک ساله
Background : The etiolog y, pathophysiology and treatment of Peyronie’s disease remain unknown. Few medical therapies have positive effect on this condition. However, penile curvature is the major symptom of Peyronie’s disease, which can be treated by surgical reconstruction. There are many surgical techniques for correcting penile deformity but ther e is the lack of a gold standard procedure...
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Peyronie's disease is a disorder caused by fibrosis of the tunica albuginea, which results in penile deformity, pain, and can be associated with erectile dysfunction. Treatment options include a variety of medical and surgical approaches, with no clear consensus as to the best treatment option. Many medical therapies have been investigated, including oral, topical, injectable, and external-ener...
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2016